Britain’s Kyle Edmund will face Andy Murray or Aljaz Bedene in the Queen’s Club quarter-finals after his second-round opponent Paul-Henri Mathieu withdrew with a wrist injury.
World number two Murray’s match with Bedene at the Aegon Championships has been brought forward to 13:15 BST.
It means there will be an all-British clash in the Queen’s quarter-finals for the first time in the Open era.
Murray last faced a compatriot in 2006, losing to Tim Henman in Bangkok.
Murray, 29, takes on Slovenia-born Bedene, who gained UK citizenship last year and, at 58th in the world, is the British number two.
“It’s amazing really. It’s been a long wait,” said Murray, who is aiming for a record fifth title at Queen’s Club.
Bedene, who has practised with Murray several times since gaining citizenship last March, had hoped to be part of the Great Britain Davis Cup squad by now.
Denied by an International Tennis Federation tribunal, Bedene hopes Thursday’s match will provide a chance to introduce himself to the British public.
“I don’t see any better court than a court in England, one of the biggest courts,” said the 26-year-old.
“I’m just going to try and play my best tennis and show myself.”
Murray will be playing his second match since Ivan Lendl returned to his coaching team, and they had their first full practice on Wednesday.
“It’s great to have him back as part of the team,” said Murray.